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子痫前期患者血内皮素、D-二聚体和瘦素水平的变化 被引量:1

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摘要 目的探讨子痫前期患者血清内皮素(endothelin,ET),D-二聚体(D-dimer,D-D)和瘦素(leptin,Lep)的水平,与子痫前期发病的关系。方法子痫前期组79例(轻度子痫前期组39例,重度子痫前期组40例),正常妊娠组40例,非孕对照组40例,采用ELISA法测定其血清中ET,D-D和Lep水平。结果轻度和重度子痫前期患者血清ET,D-D和Lep水平均明显高于正常妊娠组和非孕对照组,差异有统计学意义(均P<0.05);重度子痫前期组ET,D-D和Lep水平显著高于轻度子痫前期组,差异有统计学意义(均P<0.05);ET和D-D正相关(r=0.39,P<0.05)。结论血清ET,D-D和Lep水平增高可能在子痫前期的发病中起一定作用。
出处 《心脑血管病防治》 2014年第4期307-309,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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