功能化离子液体对2-苯乙醇萃取性能研究

Extraction Process of 2-phenylethanol with Functionalized Ionic Liquids

2-苯乙醇(2-PEA)是一种具有玫瑰花香的芳香醇,广泛应用于医药和食品工业。生物催化合成过程中,其原位萃取具有重要的意义。本研究设计合成了1-N,N-二乙基乙酰胺基-3-乙基咪唑双三氟甲基磺酰亚胺盐([EDCmim]NTf2)和1-丁基-3-甲基咪唑六氟磷酸盐([BMIM]PF6)两种离子液体,系统研究了其对2-苯乙醇萃取过程。考察了影响萃取性能的主要因素,如初始浓度、体系温度、相比等。结果表明,30 min内均可达到萃取平衡;2-苯乙醇的萃取不受转速的影响;随着相比的增加,萃取率也随之增加;随着温度的升高,萃取率随之降低;随着离子液体使用次数的增加,2-苯乙醇的萃取率也逐渐降低。

2-phenylethanol（2-PEA） is an aromatic alcohol with roses, widely used in the pharmaceutical and food industries. Its in-situ extraction during biocatalytic synthesis process has important theoretical significance. Extraction process of 2-phenylethanol has been carried out by using two kinds of ionic liquids, namely, 1-N,N-diethylac-etamide-3-ethyl imidazole bis（trifluoromethanesolphonyl） imide（[EDCmim]NTf2） and 1-butyl-3-methylimidazolium hexafluorophosphate（[BMIM] PF6）. Some important factors that affect extraction process, such as initial concentration, temperature, phase ratio etc. were investigated. Important results were listed as follows： extraction equilibrium can be reached in 30 minutes and rotation speed does not influence the extraction efficiency. Larger phase ratio gets higher extraction efficiencies, however, taken into account of the cost and extraction efficiency, proper phase ratio should be chosen. Higher temperature is not beneficial for the extraction process, which means that it is an exothermic one. With increasing frequency of use of ionic liquids, extraction efficiency of 2-phenylethanol is gradually decreased. This research will provide a new method for the extraction 2-PEA.