福建省新生儿筛查中心参加台湾葡萄糖-6-磷酸脱氢酶室间质量评价分析

Analysis of external quality assessment of Taiwan glucose-6-phosphate dehydrogenase being participated by Fujian Neonatal Screening Center

目的分析参加台湾葡萄糖-6-磷酸脱氢酶（G6PD）室间质量评价结果,以了解该项目的质控质量。方法收集2011-2012年参加台湾预防医学基金会组织的室间质量评价的单位中使用与福建省新生儿筛查中心相同实验方法的实验室（2011年14家、2012年18家）12个批次120个样本的测定结果,并对结果进行定量及定性的描述和分析。定量分析采用评价限法和Z比分数法,定性分析公式为该项目的可接受结果数/该项目总测定样本数×100%。结果评价限法分析显示12个批次中有11次结果可接受率〉80%;而Z比分数法分析12个批次结果可接受率均〉80%。定性分析显示可接受率为100%。结论定量分析评价中,Z比分数法即使在测量值较低浓度值样本的,也能有较好的评价能力,是评价限法的补充。

Objective In order to understand the external quality assessment of Taiwan glucose-6-phosphate dehydrogenase（ G6PD）,to analyze the results from 2011 to 2012. Methods The results from other laboratories using the same experiment method to deal with the external quality assessment samples from the Preventive Medicine Foundation in Taiwan from 2011 to 2012（ 2011： 14 laboratories,2012： 18 laboratories）. The quantitative and qualitative methods were used to describe and analyze the measurement results including 12 batches of 120 samples from2011 to 2012. Results In the quantitative analysis,2 statistical methods were used to analyze the results. The acceptable rate of 11 results was 〉80% by evaluation limit law,and the acceptable rate was 〉80% by Z-score method.In qualitative analysis,the acceptable rate was 100%. Conclusions In the quantitative analysis,Z-score method even in the measurement of low-density samples also can have a good evaluation ability,and it is a complement to the evaluation limit law.