伴肺部阴影的嗜酸粒细胞增多症

Pulmonary infiltrates with eosinophilia

嗜酸粒细胞(EOS)增多同时伴有肺部浸润影被称为嗜酸粒细胞性肺病(ELD),它是一组异质性疾病,可局限于肺部或侵犯全身多个系统。该类疾病的特点为肺部阴影、肺泡EOS增多,伴或不伴外周血EOS增高。根据病因主要分为原发性、继发性和偶伴EOS增多的其他疾病。临床表现轻重不一,正确诊断依赖于详细的病史询问、体格检查,并结合临床、影像、实验室检查结果。糖皮质激素是治疗ELD的主要药物,疗程和剂量需个体化。

Pulmonary Infiltrates with eosinophilia, clinically referred to as eosinophilic lung diseases （ELD）, are a heteroge- neous group of disorders characterized by pulmonary infiltration associated with alveolar eosinophilia with or without periph- eral eosinophilia. They are classified generally as primary ELD, secondary ELD, and other diseases occasionally associated with eosinophils. Clinical manifestation of these disorders can be varied, and their presentation can be mild or fatal. Accurate diagnosis is based on a full history and examination, along with clinical manifestations, radiological imaging and laboratory findings. Corticosteroids are the mainstay of treatment for ELD and most patients will require prolonged courses of daily ster- oids. The dose and use duration of eorticosteroids should be individualized.