AIP和IMT与缺血性脑卒中的相关性分析

The relationship between atherogenic index of plasma,carotid intima-media thickness and ischemic stroke

目的探讨血浆致动脉硬化指数(AIP)及颈内动脉内中膜厚(IMT)与缺血性脑卒中发生的关系。方法选择经头部CT和(或)MRI确诊为缺血性脑卒中患者70例及健康体检者70例,采用多普勒超声检测入组对象IMT、总胆固醇(TC)、低密度脂蛋白(LDL-C)、甘油三酯(TG)及高密度脂蛋白(HDL-C),计算出AIP,并进行分析。结果与健康对照组相比,缺血性脑卒中组患者IMT、TC、TG、LDL-C及AIP值明显升高,而HDL-C下降,差异有统计学意义(P<0.05);IMT与AIP呈正相关(r=0.514,P=0.001)。结论 AIP与IMT与缺血性脑卒中的发生密切相关。

Objective To investigate the relationship between atherogenic index o{ plasma, carotid intima-media thickness and isehemic stroke. Methods Intima-media thickness（IMT） were examined with color Doppler ultrasound in 70 patients with ischemic stroke confirmed by cranial CT and（or） MRI and 70 subjects for health examination as controls;the level of triglycer- ide（TG）, total cholesterol（TC）, low-density lipoprotein cholesterol（LDL-C）, high density lipo-protein cholesterol（HDL-C） were detected for all subjects and atherogenic index of plasma（AIP） were determined in 70 patients with ischemic stroke and 70 subjects as controls. Results The levels of IMT, TC, TG, LDL-C and AIP increased significantly in patients with ischemic stroke, and the levels of HDL-C decreased significantly（P〈0.05）. IMT was correlated with AIP（r= 0.514, P = 0.001 ）. Con- clusion The development of ischemic stroke is closely correlated with the carotid IMT and AIP.