舒利迭在老年慢性阻塞性肺疾病致呼吸衰竭抢救中的价值研究

Research on the effect of seretide on rescuing elderly patients with chronic obstructive pulmonary disease and respiratory failure

目的:研究舒利迭在老年慢性阻塞性肺疾病致呼吸衰竭抢救中的临床价值。方法:选取98例老年慢性阻塞性肺疾病致呼吸衰竭患者资料,随机分为观察组(舒利迭联合无创正压通气治疗)和对照组(单纯使用无创正压通气治疗)。检测应激反应指标及血气指标并分析其相关性。结果:治疗后观察组患者的肾上腺素、去甲肾上腺素、肾素、血管紧张素Ⅱ水平以及动脉二氧化碳分压低于对照组,动脉血氧分压高于对照组;动脉血氧分压与肾上腺素、去甲肾上腺素、肾素以及血管紧张素Ⅱ水平呈负相关,动脉二氧化碳分压与其呈正相关。结论:舒利迭可以有效降低患者的应激水平,改善血气水平,且应激水平与动脉血氧分压呈负相关,与动脉二氧化碳分压呈正相关。

Objective：To study the effect of Seretide on rescuing elderly patients with chronic obstructive pulmonary disease and respiratory failure.Methods：Ninty-eight cases elderly patients with chronic obstructive pulmonary disease and respiratory failure in our hospital were enrolled and randomly divided into observation group given seretide combined noninvasive positive pressure ventilation and control group given Simple noninvasive positive pressure ventilation.Then stress response index and blood gas were detected and their correlation was analyzed.Results：After treatment,E,NE,R and AT Ⅱ levels and PaCO2 of observation group were lower than control group,PaO2 level was higher than control group; PaO2 was negatively correlated with E,NE,R,AT Ⅱ levels,PaCO2 was positively correlated with them.Conclusion：Seretide can reduce patients＇ stress levels,improve blood gas levels,and stress level was negatively correlated with PaO2 and positively correlated with PaCO2.