摘要
目的:观察参芪扶正注射液对晚期非小细胞肺癌(NSCLC)姑息治疗患者免疫功能及生存质量的影响。方法:132例晚期NSCLC姑息治疗患者,每人每日给予参芪扶正注射液250 mL,静脉滴注,14~21 d为1个疗程,至少应用1个疗程。观察用药前后患者CD3+、CD4+、CD8+T细胞、KPS评分及体质量的变化情况。结果:参芪扶正注射液能升高患者CD4+、CD4+/CD8+值,降低CD8+值,明显提高患者体质量及KPS评分状态。结论:参芪扶正注射液能改善NSCLC晚期姑息治疗患者的免疫功能、提高生存质量。
Objective:To investigate the effect of Shenqi Fuzheng Injection on the quality of life and immune function in advanced NSCLC patients with palliative treatment. Methods :132 patients of advanced NSCLC patients with palliative treatment were treated with intravenous infusion Shenqi Fuzheng Injection 250 mL per person per day, 14 to 21 days as a course of treatment, at least one course. CD3+ , CD4+ , CD8+ T cell, KPS scores and weight changes before and after treatment were observed. Results : Shenqi Fuzheng Injection can increase levels of CD3+ , CD4+ ,CD4+/CD8 + ,decrease CD8 + , significantly increase patients' weights and KPS score. Conclusion: Shenqi Fuzheng Injection can enhance the immune function, and improve the quality of life in patients with advanced NSCLC undergoing palliative treatment.
出处
《中医学报》
CAS
2014年第8期1097-1098,共2页
Acta Chinese Medicine
基金
郑州市科技局科技发展计划(编号:20130532)
关键词
非小细胞肺癌
参芪扶正注射液
免疫功能
生存质量
姑息治疗
non-small cell lung cancer
shenqi fuzheng injection
immunologic function
quality of life
palliative treatment