保和丸合二陈汤加减辨治小儿食积咳嗽临床疗效观察

Clinical Observation on Baohe Pill and Erchen Decoction for Treating Pediatric Patients with Dyspepsia Cough

目的:观察用保和丸联合二陈汤加减辨治小儿食积咳嗽的临床效果。选取2011年3月—2013年2月就诊于我院的经中医临床辨证为食积咳嗽的小儿患者123例,随机分为对照组60例和观察组63例。对照组患者给予小儿消积止咳口服液治疗,3次/d;观察组患者给予由保和丸和二陈汤加减而成的中药汤剂口服进行治疗,1剂/d;治疗后观察两组小儿患者治疗前后咳嗽、喉中痰鸣音、纳呆腹胀、便秘便臭、口臭、手足心热等临床症状的改善情况及证候积分的变化情况,比较两组治疗的有效率。结果:对照组有效率为71.7%,观察组有效率为92.1%,对照组的有效率明显低于观察组,2组有效率比较,差异有统计学意义(P<0.05)。2组患者经治疗后咳嗽、喉中痰鸣音、纳呆腹胀、便秘便臭、口臭、手足心热等临床症状均较治疗前有所改善,证候积分均有所下降,以观察组的改变程度尤为明显,差异有统计学意义(P<0.05)。结论:保和丸和二陈汤是功可消食导滞、理气和中、燥湿化痰的经典方剂。临床应用广泛,用于治疗食积咳嗽患儿能有效缓解患儿咳嗽、喉中痰鸣音、纳呆腹胀、便秘便臭、口臭、手足心热等临床症状,疗效确切,值得临床广泛运用。

Objective： To investigate the clinical efficacy of treating pediatric patients with dyspepsia cough with Baohe Pill and Erehen Decoction. Methods： 123 pediatric patients with dyspepsia cough cases were randomly divided into a control group of 60 cases and a observation group of 63 cases from March 2011 to February 2013. Patients in the control group were treated with children cough oral liquid deposition for oral treatment, 3 times / day ; while patients in the observation group were treated with self-made decoction-- Baohe Pill and Erchen Decoction for treatment, 15 days for a course. We observed the clinical symptoms of the patients such as cough, gurgling with sputum, indigestion and loss of appetite, constipation, feverishness in palms and soles pretherapy and post-treatment, and compared the clinical efficacy of two groups of patients after one course of treatment. Results： The efficiency for patients in the control group was 71.7%, while for patients in the observation group it was 92.1%, which was clearly higher than that of the control group. The clinical efficacy of the two groups was significantly different （ P〈0.05 ）. The clinical symptoms of the patients in two groups were improved clearly. The degree of change in the observation group was more pronounced. The comparison of the two groups was significantly different （ P〈0.05 ）. Conclusion ： The Baohe Pill and Erehen Decoction are classical TCM prescriptions, which have the function of promoting digestion, promoting the circulation of qi, tonifying spleen and stomach, drying damp and eliminating phlegm, which can effectively relieve the clinical symptoms of the patients such as cough, gurgling with sputum, indigestion and loss of appetite, constipation, feverishness in pahns and soles, has satisfactory results and is worthy of further research and development.