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环境内分泌干扰效应的研究历程及意义

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摘要 环境中存在着大量人工合成的化学物,这些人类创新产物可能会干扰人体内分泌系统的正常的功能,导致内分泌系统肿瘤,不孕不育,甚至会影响到人类的生存繁衍,他们属于环境内分泌干扰物。人类努力探究这些环境内分泌干扰物的环境浓度及其对生物体的作用机理,以便为管理它们提供依据。但是随着内分泌干扰物的种类及数量越来越大,仅依赖传统毒理学的方法即利用动物实验及经验对化合物的毒性进行评定远远不能满足人类对于管理它们所需数据的需求。随着科学的发展,生物学和计算机等学科也得到迅猛发展,从而也推动了传统毒理学向计算毒理学的转变,使化合物性质的预测更加便利。
作者 张辉 刘玉玲
出处 《科技视界》 2014年第23期290-291,300,共3页 Science & Technology Vision
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