先天性单侧附件缺如21例的临床特征及发病机制探讨

Pathogenesis and clinical characteristics of 21 patients with congenital unilateral uterine adnexa absence

目的 总结国内21例单侧附件缺如的妊娠结局,并探讨其发病机制. 方法 检索国内医学期刊报道的20例及本文新报道的1例,从年龄、月经史、生育史、盆腔粘连、伴其他器官发育异常、染色体检查及确诊途径等方面进行总结分析.结果 21例年龄20～46岁患者全部是在开腹或腹腔镜手术中得以确诊.月经史：除3例无记载外,其余18例中17例正常,1例月经不规律.生育史：除2例没有记载外,其余19例中15例有妊娠史,3例为原发不孕,1例未婚.本文资料左/右附件缺如（7/14）的比例为1：2. 结论 附件缺如应为女性生殖器官先天性发育异常所导致的一种结局,如果一侧附件正常,妊娠率与正常女性相近.

Objective：To summarize clinical characteristics of 21 patients with unilateral uterine adnexa absence,and investigate its pathogenesis.Methods：The data of twenty patients retrieved from Chinese medical literatures and a new patient＇ data presented in this paper were summarized and analyzed.Results：All of 21 patients were diagnosed by laparotomy or laparoscopy.The Patients were 20 to 46 years old.Menstrual history included normal （n =17）,irregular （n =1）,no record （n =3）.Childbearing history included pregnancy （n =15）,primary infertility（n =3）,singlehood （n =1）,and no record （n =2）.Theabsence of uterine adnexa involved either left（n =7）or right（n =14）side,and the ratio of left to right absent adnexa was 1：2（7/14）.Conclusions：The unilateral absence of uterine adnexa is a congenital anomaly of reproductive organs.If one side of adnexa is normal,the pregnancy rate is close to normal women.