2μm激光与等离子电切治疗良性前列腺增生疗效比较的Meta分析

Comparison of 2μm laser resection and plasmakinetic resection for BPH:a Meta-analysis

目的:比较2μm激光与等离子电切治疗良性前列腺增生(BPH)的疗效,系统评价2μm激光临床应用效果,为临床提供参考依据。方法:收集已发表的关于2μm激光和等离子电切治疗BPH的国内外文献,针对结果进行统计学综合分析(Meta)。终末指标采用SMD值及95%CI进行比较分析,统计学处理采用Revman5.0软件。结果:共7篇文献符合纳入标准,对2μm激光组的463例和等离子电切组的608例进行分析。Meta分析显示:1等离子电切组手术时间少于2μm激光组,差异有统计学意义(P<0.01);22μm激光组术中出血量小于等离子电切组,差异有统计学意义(P<0.01);32μm激光组术后留置尿管时间少于等离子电切组,差异有统计学意义(P<0.01);42μm激光组膀胱冲洗时间少于等离子电切组,差异有统计学意义(P<0.01);52μm激光组住院时间少于等离子电切组,差异有统计学意义(P<0.01)。结论:2μm激光具有出血少、创伤小、术后恢复快等优势,治疗BPH安全可靠。

Objective：To compare the efficacy of 2μm laser resection and plasmakinetic resection for BPH,and to evaluate clinical effects of 2μm laser so as to provide clinical reference.Method：We retrieved published comparative studies of 2μm laser resection and plasmakinetic resection for BPH,and pooled the data from eligible studies（Meta-analysis）.Standardized mean difference and its 95% confidence interval（CI）were used as the measurement parameter of efficacy comparison.The statistical analyses were performed using Revman 5.0software.Result：Five trials included 463 patients treated with 2μm laser resection and 608 cases treated with plasmakinetic resection.Pooling data showed：1operative time of plasmakinetic procedure was less than 2μm laser resection（P 〈0.01）;2intraoperative blood loss of 2μm laser group was less than plasmakinetic group,which the difference was statistically significant（P 〈0.01）;3comparing postoperative indwelling catheter time between the two groups,2μm laser has a less time than the plasmakinetic group,which the difference was statistically significant（P〈0.01）;4bladder irrigation time was significantly different between two groups,2μm laser group has a shorter time（P 〈0.01）;5hospital stay of 2μm laser group was shorter than the plasmakinetic group,and the difference was statistically significant（P〈0.01）.Conclusion：The treatment of 2μm laser is safe and reliable to BPH with less blood loss,fewer traumas,quicker recovery and other advantages.