基于冠脉灌注压的胸外按压闭环控制计算机仿真研究

Closed-loop Control for Chest Compression Based on Coronary Perfusion Pressure:A Computer Simulation Study

本文介绍的胸外按压闭环控制是在胸外按压心肺复苏中引入冠脉灌注压(CPP)标准来调节按压深度的自动控制技术。它采用个性化急救方案,突破了以统一的按压深度和频率为标准评价胸外按压质量而忽视患者个体差异的局限性,对提高胸外按压效率有着重要意义。本研究重建了Charles F.Babbs人体血液循环模型,添加了CPP检测模块,设计了闭环胸外按压自动控制器,并进行了计算机仿真实验。实验表明,基于模糊控制的闭环胸外按压控制器,不但调节时间短,超调量小,而且几乎无振荡现象发生;在有效调节和稳定维持CPP方面,均表现出了优异的控制性能。

Abstract： In this study, a closed-loop controller for chest compression which adjusts chest compression depth accord ing to the coronary perfusion pressure （CPP） was proposed. An effective and personalized chest compression method for automatic mechanical compression devices was provided, and the traditional and uniform chest compression standard neglecting individual difference was improved. This study rebuilds Charles F. Babbs human circulation model with CPP simulation module and proposes a closed-loop controller based on a fuzzy control algorithm. The perform- ance of the fuzzy controller was evaluated and compared to that of a traditional PID controller in computer simulation studies. The simulation results demonstrated that the fuzzy closed-loop controller produced shorter regulation time, fewer oscillations and smaller overshoot than those of the traditional PID controller and outperforms the traditional PID controller in CPP regulation and maintenance.