人羊膜应用的研究进展

Research Progress of Human Amniotic Membrane Applications

近百年的应用研究历史证实人羊膜内包含多达几十种生物活性物质,具有抗炎、抗菌、抗病毒、抑制新生血管形成及促进细胞凋亡等作用,在治疗烧伤、创伤、眼部损伤、皮肤病等疾病方面取得了显著疗效。近年来羊膜及羊膜细胞在组织工程皮肤、血管构建、生物支架材料及生物缓释材料等方面的研究取得了长足进步。羊膜及羊膜细胞在生物医药领域也展露出优势和魅力,具有一定的科学研究价值和广阔的应用前景。

Application research on human amniotic membrane has been carried out for nearly a hundred years and people found that there were more than dozens of kinds bioactive substances in the amniotic membrane. It has been proved that the amniotic membrane has a lot of functions, such as anti-inflammatory, anti-bacterial, anti-virus, antiangiogenic and promoting cell apoptosis, and so on. As effective treatments, amniotic membrane has been used for adjunctive therapy of burns, trauma, ophthalmic damage, dermatopathya. Recent advances of amniotic membrane and amniotic membrane-derived cells research have led to enormous progress in skin tissue engineering, vascular tissue engineering, biological scaffold material, and biological sustained-release materials. Amniotic membrane and amniotic membrane derived cells have a significant advantage and unique charm in medical field. Therefore, they have higher research value and broad prospects in the applications.