腰腹联合手法治疗腰椎间盘突出症的生化指标分析

Biochemical Analysis of Combined Lumbo-abdominal Manipulation in the Treatment of Lumbar Intervertebral Disc Herniation

目的:观察腰腹部联合手法治疗腰椎间盘突出症的生化指标。方法:将75例患者随机分为3组,每组25例:对照组采用常规输液和卧床休息治疗;治疗1组采用传统手法治疗配合常规输液和卧床休息治疗;治疗2组采用腰腹部联合手法配合常规输液和卧床休息治疗。3组患者分别于治疗前与治疗结束后进行血浆血栓素B2(TXB2)、6-酮-前列腺素F1α(6-K-PGF1α)、白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)的测定。结果:3组治疗后TXB2、IL-1β、TNF-α含量均明显降低,6-K-PGF1α含量治疗后较治疗前明显升高。对照组与治疗1组比较差异无统计学意义(P>0.05);治疗2组与对照组、治疗组比较差异有统计学意义(P<0.05)。结论:本研究中腰腹联合手法治疗后生化指标有明显改善。说明腰腹联合手法可加速血液循环,促进机体新陈代谢,有利于神经根水肿的消退。这可能是其效果优良的作用机制之一。

Abstract Objective：To observe the biochemical result of combined lumbo-abdominal manipulation in the treatment of lum- bar intervertebral disc herniation. Methods：75 patients were randomly divided into 3 groups. 25 patients underwent conven- tional medication and bed rest therapies in control group. 25 patients underwent traditional manipulation combined conven- tional medication and bed rest therapies in treatment group 1; 25 patients underwent combined lumbo-abdominal manipula- tion and conventional medication and bed rest therapies in treatment group 2. TXB2, IL-1β ,TNF-α and 6-K-PGFlo were taken before and after treatment to assess the therapeutic effects. Results：TXB2, IL-1β, TNF-α levels were reduced evi- dently in all three groups and 6-K-PGF-α level increased evidently after treatment. There was no difference between the con- trol group and the treatment group 1 （P〉0.05）. There was significant difference between the control group and the treatment group 2（P0.05）. Conclusion：Improved biochemical indicator shows that combined lumbo-abdominal manual therapy can accelerate the blood circulation of patients, promote metabolism and relieve the edema of nerve root. Perhaps it is one of the main mechanisms.