自身抗体检测进入定量检测时代

New era in autoantibodies detection： quantitation

自身抗体是用于辅助诊断自身免疫性疾病（AID）的重要实验室指标,其检测方法已不同程度实现了定量或半定量.随着检测技术的发展,高通量定量检测技术已成为自身抗体检测的重要手段和发展趋势.与定性检测相比,定量检测某些自身抗体不仅可以更好地辅助诊断AID,而且可以更有效地反映病情、预测疾病的发生和预后、监测治疗效果.因此,尽管自身抗体定量检测仍存在诸多挑战,但毫无疑问自身抗体已进入定量检测时代.

Autoantibodies are useful laboratory parameters for diagnosis of autoimmune diseases （AID）.Methods for the detection of autoantibodies have achieved quantitative or semi-quantitative to some extent.Furthermore,with the development of detection technology,high-throughout and quantitative technology has been the trend in autoantibody measurement.Compared with qualitative results,the quantitative ones may provide more values for diagnosis,prediction,prognosis and therapeutic monitoring for AID.Therefore,although quantitative technology of autoantibodies is still faced a number of challenges,the detection for autoantibodies has come into the era of quantitation.