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磁共振温度成像技术研究进展 被引量:6

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摘要 肿瘤热疗是利用物理能量加热人体局部或全身,使肿瘤组织温度上升到有效治疗温度,并维持一定的时间,以达到使肿瘤细胞凋亡但不损伤正常组织的一种治疗方法.一般正常组织可以长时间耐受42~43℃高热,加热到57~60℃(蛋白质变性阈值)数秒后组织即开始凝结坏死,即使温度低于该值,延长加热时间也会杀死组织.特别在高强度聚焦超声(high intensity focused ultrasound,HIFU)热疗中,靶组织的温度上升速度可以达到3℃/s,空间分辨率低于2 mm3即会产生较大的测温误差[1],因此,加热过程中对组织温度的实时检测十分必要.
出处 《中国医学影像学杂志》 CSCD 北大核心 2014年第7期547-550,553,共5页 Chinese Journal of Medical Imaging
基金 国家自然科学基金项目(81271568)
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参考文献32

  • 1Todd N, Payne A, Parker DL. Model predictive filtering for improved temporal resolution in MRI temperature imaging. Magn Reson Med, 2010, 63(5): 1269-1279.
  • 2Germain D, Chevallier P, Laurent A, et al. MR monitoring of tumour thermal therapy. MAGMA, 2001, 13(1): 47-59.
  • 3Bloembergen N, Purcell EM, Pound RV. Relaxation effects in nuclear magnetic resonance absorption. Physical Review, 1948, 73(7): 679-712.
  • 4Parker DL, Smith V, Sheldon P, et al. Temperature distribution measurements in two-dimensional NMR imaging. Med Phys, 1983, 10(3): 321-325.
  • 5Cline HE, Schenck JF, Watkins RD, et al. Magnetic resonance- guided thermal surgery. Magn Reson Med, 1993, 30(1): 98-106.
  • 6Gcnsler D, Fidler F, Ehses P, et al. MR safety: liast T1 thermometry of the RF-induced heating of medical devices. Magn Reson Med, 2012, 68(5): 1593-1599.
  • 7Young IR, Hand JW, Oatridge A, et al. Modeling and obseration of temperature changes in vivo using MRI. Magn Reson Med, 1994, 32(3): 358-369.
  • 8Graham S J, Bronskill M J, Henkelman RM. Time and temperature dependence of MR paralneters during thermal coagulation of ex vivo rabbit muscle. Magn Reson Med, 1998, 39(2): 198-203.
  • 9Daniel BL, Butts K, Block WF. Magnetic resonance imaging of frozen tissues: temperature-dependent MR signal characteristics and relevance for MR monitoring of cryosurgery. Magn Reson Med, 1999, 41(3): 627-630.
  • 10Hindman JC. Proton resonance shift of water in the gas and liquid states. J Chem Phys, 2004, 44( 12): 4582-4592.

同被引文献41

  • 1俞开潮,王国平,丁尚武,叶朝辉.用于磁共振成像对比增强的造影剂研发进展[J].波谱学杂志,2004,21(4):505-525. 被引量:18
  • 2桑林琼,邱明国,王莉,张静娜,张晔.基于统计阈值的脑肿瘤MRI图像的分割方法[J].生物医学工程研究,2010,29(4):237-239. 被引量:11
  • 3周芳芳,樊晓平,叶榛.均值漂移算法的研究与应用[J].控制与决策,2007,22(8):841-847. 被引量:59
  • 4Al-Bataineh O,Jenne J,Huber P.Clinical and future applications of high intensity focused ultrasound in cancer.Cancer Treat Rev,2012,38(5):346-353.
  • 5Phenix CP,Togtema M,Pichardo S,et al.High intensity focused ultrasound technology,its scope and applications in therapy and drug delivery.J Pharm Pharm Sci,2014,17(1):136-153.
  • 6Isern J,Pessarrodona A,Rodriguez J,et al.Using microbubble sonographic contrast agent to enhance the effect of high intensity focused ultrasound for the treatment of uterine fibroids.Ultrason Sonochem,2015,27:688-693.
  • 7Huang CW,Sun MK,Chen BT,et al.Simulation of thermal ablationby high-intensity focusedultra sound with temperature-dependent properties.Ultrason Sonochem,2015,27:456-465.
  • 8Hoogenboom M,Eikelenboom D,Den Brok MH,et al.Mechanical high-intensity focused ultrasound destruction of soft tissue:working mechanisms and physiologic effects.Ultrasound Med Biol,2015,41(6):1500-1517.
  • 9Niu D,Wang X,Li Y,et al.Facile synthesis of magnetite/perfluorocarbon co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation.Adv Mater,2013,25(19):2686-2692.
  • 10Chen Y,Chen H,Shi J.Nanobiotechnology promotes noninvasive high-intensity focused ultrasound cancer surgery.Adv Healthc Mater,2015,4(1):158-165.

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