人牙的酸蚀损伤抑制及牙齿再矿化

Erosion prevention and remineralization of human teeth

背景:随着酸性饮料大量摄入,牙齿酸蚀问题日趋严重,酸蚀不仅导致牙齿表面硬组织的直接丧失,还会引起牙齿过度磨损,对口腔健康造成了严重威胁。目的:总结国内外文献关于人牙酸蚀、抑制牙酸蚀及牙齿再矿化方面的研究进展。方法:由第一作者检索1990至2013年CNKI、Elsevier以及Wiley数据库有关人牙、酸蚀、抑制以及再矿化等方面的文献,排除重复性及陈旧性文献,纳入58篇进行分析。结果与讨论:国内外关于牙齿酸蚀的研究大致分为:牙齿酸蚀病症与病因的临床观察;常见饮料酸味添加剂对牙齿酸蚀损伤程度的对比研究;牙齿酸蚀的抑制与修复行为研究。其中,牙齿酸蚀的抑制研究是现阶段的热点与难点,现有研究多通过调控口腔环境、降低酸的腐蚀能力、提高牙齿抵抗酸蚀的能力等3个方面来抑制人牙酸蚀。在口腔环境中,牙齿的酸蚀与摩擦磨损问题密不可分,进一步研究应该多关注牙齿酸蚀与摩擦磨损的耦合作用。

BACKGROUND： With the consumption of acidic beverages, related to direct loss of dental hard tissue, and causes denta health, dental erosion becomes more serious. Erosion is over-abrasion, thus great threatening the dental OBJECTIVE： To review the research work on the erosion of human teeth, erosion prevention, and teeth remineralization. METHODS： A computer-based online retrieval of CNKI, Elsevier and Wiley databases between 1990 and 2013 was performed for articles abut human teeth erosion, erosion prevention and teeth remineralization. After repeated or old literatures were excluded, 58 literatures were included in the analysis. RESULTS AND CONCLUSION： Current studies on dental erosion included three aspects, firstly, clinical observation of the symptoms and cause of dental erosion; secondly, the erosiveness of common acidic agents; and thirdly, the prevention of dental erosion. Many researchers focused on the prevention of dental erosion. It was suggested that dental erosion could be prevented through adjusting and controlling oral environment, enhancing the erosiveness of acidic beverages, and increasing the anti-erosion capacity of teeth. It should be noted that tooth erosion and friction/wear often occur simultaneously in the mouth. Therefore, future research should pay attention to the interaction mechanism of erosion, friction and wear of human teeth.