重症急性胰腺炎局部并发症的中西医结合微创化治疗

Mini-invasive Treatment with TCM and Western Medicine for Local Complications of Severe Acute Pancreatitis

目的:探讨中西医结合微创化治疗重症急性胰腺炎局部并发症中的有效性。方法:将我科收治的130例重症急性胰腺炎人全部按照重症急性胰腺炎中西医结合诊治常规治疗,出现局部并发症75例。随机分组进行了开放性手术(37例)或微创清创引流术(38例),并比较开放性手术与微创清创引流患者的病死率、手术次数、住院时间、总费用等指标。结果:死亡率相比,微创引流组患者死亡率(2.6%)明显低于开放手术组(10.8%)(P<0.05);手术次数两组相比,微创组穿刺引流次数(3.33±0.58)多于开放手术组(2.52±0.82),但无统计学意义(P>0.05)。住院时间两组相比微创组有增加趋势[(53.3±37.6)d,(44.5±28.5)d],但无统计学差异(P>0.05)。住院费用两组相比微创组(37 661.36±21 732.00)元显著低于常规开放手术组(54 423.83±45 263.06)元(P<0.05)。结论:中西医结合微创化治疗重症急性胰腺炎局部并发症具有一定的优势,能够降低患者死亡率和住院费用。

Objective To explore the effect of mini-invasive treatment with TCM and western medicine for local complications of severe acute pancreatitis（SAP）. Methods Total one hundred and thirty SAP patients admitted in Nankai Hospital were treated with combination of TCM and western medicine. Seventy-five patients who had complications were divided randomly into open operation group and mini invasion group. The morbidity, the number of operation, hospitalization time and hospital cost were compared between groups. Results Mini invasion group showed lower morbidity and hospital costs2.6%,（37 661.36±21 732.00） compared with open operation group（10.8%,54 423.83±45 263.06）（P〈0.05 No significant difference was found on the number of operation and hospitalization time（3.33±0.58 vs 2.52±0.82, 53.3±37.6） vs （44.5±28.5） between groups（P〉 0.05） Conclusion Mini-invasive treatment of TCM and western medicine has advantages for local complications of SAP and shows lower mortality and hospital costs.