卵巢成熟畸胎瘤患者术后发热相关因素研究

Research on Related Factors for Postoperative Fever in Patients with Ovarian Mature Teratoma

目的探讨卵巢成熟畸胎瘤患者术后发热相关因素。方法对2010年9月-2013年8月经手术治疗且病理确诊为卵巢成熟畸胎瘤患者进行研究,将88例术后发热患者纳入发热组,100例术后无发热的患者纳入对照组,对两组病历资料进行回顾性病例对照研究。结果发热组和对照组住院时间分别为(5.68±1.53)、(3.28±1.18)d,开腹手术构成比分别为38.64%(34/88)、20.00%(20/100),瘤体最大径线分别为(6.65±3.07)、(5.33±1.87)cm,两组比较差异均有统计学意义(P<0.05);两组在年龄、体质量指数、术前体温、术前CA199、术前瘤体扭转、术前使用抗生素、瘤体特征(有无骨质、是否多房、是否双侧)、手术时间、术中出血量、盆腔粘连、安放腹腔引流管等方面差异均无统计学意义(P>0.05)。结论卵巢成熟畸胎瘤患者术后发热与手术方式、瘤体大小相关,且影响住院时间;应当加强妇科检查,对于成熟畸胎瘤的早期发现和手术方式的合理选择均可减少术后发热的发生,从而缩短住院时间,节省医疗资源。

Objective To explore the related factors for postoperative fever in patients with ovarian mature teratoma. Methods A case-control study was conducted, and the subjects were patients with ovarian mature teratoma who had undergone surgical treatment in the hospital where the author works during September 2010 to August 2013. Eightyeight cases diagnosed as ovarian mature teratoma with postoperative fever were included in the case group and 100 cases diagnosed as ovarian mature teratoma without postoperative fever were included in the control group. The medical records of the two groups were analyzed retrospectively. Results Hospital stay of the case group and the control group was（5.68 ± 1.53） and（3.28 ± 1.18） days, respectively. The laparotomy ratio was 38.64%（34/88） and 20.00%（20/100）; the tumor diameter was（6.65 ± 3.07） cm and（5.33 ± 1.87） cm, respectively. The difference in the above indicators between the two groups was significant（P〈0.05）. There was no significant difference in age, body mass index, body temperature before surgery, preoperative CA199, preoperative tumor torsion, preoperative antibiotics, tumor characteristics（bone, multiroom, bilateral）, operative time, blood loss, pelvic adhesions, placing drainage tubes between the two groups（P〈0.05）. Conclusions Postoperative fever of ovarian mature teratoma is related to surgical approach and tumor size. Hospital stay is associated with postoperative fever. We should strengthen the gynecological examination. Early detection and reasonable choice of surgical procedures can reduce the incidence of postoperative fever, thus shorten the hospital stay and save medical resources.