血管内皮生长因子与子宫内膜异位症发病关系的研究进展

The research of relations between Vascular endothelial growth factor and Endometriosis

子宫内膜异位症(EM)是妇科的一种常见病和多发病,虽为良性病变,但具有远处转移和种植能力。EM的内膜血管生成受多种因素的影响,而血管内皮生长因子(VEGF)是目前公认的关键性的促血管形成因子,VEGF对正常血管生成及病理性血管形成均起重要的生物调节作用,在EM的发生、发展及预后中起着重要的作用。本文对VEGF与EM发病关系的研究进展进行阐述。

Objective：Endometriosis（EM）is a common and frequently-occurring disease in gynecology.Although it is benign lesions,it adopts metastasis and growing capacity.Endometriosis endometrial angiogenesis are affected by many factors,while the vascular endothelial growth factor（VEGF）is recognized a key pro-angiogenic factors.VEGF plays an important biological regulator role in the formation of both blood vessels and pathological angiogenesis,and also plays a role in the occurrence of endometriosis,development and prognosis.In this paper,the research progress of the relationship between vascular endothelial growth factor and pathogenesis of endometriosis were described