优化的2D TOF和并行采集技术在颈动脉血管成像中的应用

The Clinical Application of an Optimizing 2D TOFMRA and Parallel Acquisition Tomography in Carotid Angiography

目的探讨优化改良的2D TOF MRA和并行采集技术与传统的2D TOF MRA技术相比较在颈动脉血管成像中的应用。方法 2013年1月至10月入选152例可疑颈部动脉病变的患者随机分为两组:传统技术组:行传统的2D TOF MRA扫描(采用设备自带原始扫描序列及参数),扫描时间5min54s;优化组:采用改良后扫描方法,即TR TE时间及层厚不变,改变偏转角度数为40°,增大FOV,增加扫描层数为110层,用GRAPPA并行采集技术缩短扫描时间为4min37s。图像经由两名高年资MR诊断医师对图像质量及病变显示情况进行评价:优质图像为Ⅰ级,劣质图像为Ⅲ级。结果完成152例患者1368支颈动脉段血管成像,传统组68例患者612支血管图像质量分级为:Ⅰ级405支(66.2%),Ⅱ级191支(31.2%),Ⅲ级16支(2.9%)。优化组84例患者756支血管图像质量分级为:Ⅰ级673支(89%),Ⅱ级83支(11%),Ⅲ级0支(0%)。优化组I级血管成像率显著高于传统组(89%vs.66.2%;P<0.001),III级血管图像显著低于传统组(0 vs.2.9%;P<0.001)。结论在颈动脉血管成像中应用优化2D TOF MRA扫描参数和并行采集技术可以缩短扫描时间,提高颈动脉图像高质量,具有良好的临床应用价值。

Objective To determine the clinical application of an optimizing 2D TOFMRA and parallel acquisition tomography in carotid angiography.Methods From January 2013 to December 2013, a series of consecutive patients with equivocal for carotid artery disease were recruited and randomized to two groups： traditional group（receiving traditional 2D TOFMRA） and optimizing group（receiving optimizing optimizing 2D TOFMRA and parallel acquisition tomography）. The quality of image were assessed by two senior doctors and classified into classⅠ（high）, Ⅱ（median） and Ⅲ（low）. Results A total of 1368 arteries in 152 patients were imaged. In traditional group, 612 arteries in 68 patients were classified into class Ⅰ（405, 66.2%）, Ⅱ（191, 31.2%）and Ⅲ（16, 2.9%）. In optimizing group, 756 arteries in 84 patients were assessed with 673 arteries in class Ⅰ（89.0%）,83 arteries in class Ⅱ（11.0%） and0 in class Ⅲ. As compared with traditional 2D TOFMRA, more high quality images（89% vs. 66.2%; P0.001） and less low qualities images（0 vs. 2.9%,P0.001） for carotid artery were observed in optimizing group. Conclusion The optimizing method of 2D TOFMRA and parallel acquisition tomography could offer a safe and efficacy examination for carotid angiography with short scan time and improved image quality.