老年性重症社区获得性肺炎患者预后的临床分析

Predictor of in-hospital mortality in elderly patients with community acquired pneumonia

目的:探讨影响老年性重症肺炎伴呼吸衰竭患者短期预后的相关因素。方法:回顾性分析89例老年性重症社区获得性肺炎患者的临床资料,通过Logistic回归的方法寻找影响患者临床预后的相关因素。结果:老年性重症肺炎伴呼吸衰竭患者存活组与死亡组之间在谵妄的发生率、CURB-65评分及血肌酐之间有统计学差异(P<0.001)。Logistic回归分析显示谵妄与高CURB-65评分是患者死亡的独立危险因素。两组患者之间基础疾病状况无显著统计学差异。结论:对于老年性社区获得性肺炎患者而言,谵妄与CURB-65高分值是预测患者死亡的独立危险因素。

Objective ： To evaluate predictors of in-hospital outcome in elderly patients hospitalized for severe CAP. Methods ： In this retrospective study, consecutive patients with CAP aged more than 65 years were enrolled in LuAn hospital ICU. Clinical and laboratory characteristics were collected from electronic medical records. The end-point of the study was the occurrence of in-hospital death. 89 patients were enrolled. Results： There are signifi- cant difference in CURB-65,rate of delirium and creatinine between two groups （P〈0.001）. At multivariate analysis, independent predictors of in-hospital death were occurrence of at least one episode of delirium and CURB-65 score. Conclusion： in this cohort of elderly patients, the occurrence of delirium was highly prevalent and represented a dis- tinctive predictor of death.