藿香正气口服液制备工艺改进

Improvement of the technique to prepare oral liquid of Huoxiangzhengqi

目的改进藿香正气口服液制剂处方中广藿香油、紫苏叶油的添加工艺,得到澄清、质量合格的制剂。方法利用滑石粉的分散吸附作用,提高广藿香油、紫苏叶油的溶解性。将广藿香油、紫苏叶油加入到滑石粉中,充分研匀,加入到藿香正气口服液中充分搅拌,过滤,即得澄清制剂。结果制剂澄清,口感好,质量合格。结论该方法可行,工艺简单而稳定,且生产成本低。

Objective To obtain a clear and qualified oral liquid preparation of Huoxiangzhengqi by improving the addition methods of patchouli oil and perilla leaf oil. Methods Pulvis Talci was used to improve the solubility of patchouli oil and perilla leaf oil. Firstly, the two kinds of oil were mixed with Pulvis Talci and triturated sufficiently. Then, the mixture was mixed with the physic liquor and agitated sufficiently. At last, the clear preparation was obtained after filtration. Results The preparation was clear, well-tasted and qualified. Conclusion The improved method is feasible, simple, stabilized and economical.