摘要
抗生素的出现阻碍了致病菌的传播,但随着抗生素的广泛使用,细菌的耐药性问题越来越严重,给临床治疗带来巨大困难。细菌对β-内酰胺类抗生素的耐药问题已经引起广泛重视。致病菌能够在动物机体内定植、入侵并破坏机体的免疫系统,最终引起动物的发病,往往与其含有的毒力因子有关。近年来,随着研究的不断深入,人们发现细菌毒力的变化与其耐药性之间存在一定的关系。论文主要针对细菌的β-内酰胺类抗生素耐药和毒力之间的关系进行综述。
Antibiotics is essential in controlling infection caused by bacteria,unfortunately,the resistance of bacteria has emerged because of its extensive use,especially in beta-lactam antibiotics,which lead to a significant clinical problem worldwide in treating infections caused by bacteria.Virulence factors play a cru-cial role in its pathogenicity,particularly in permanent planting and invasion of the immune system in ani-mals.The recent studies indicated that there was a link between virulence factors and antibiotic resistance in bacteria.In this paper,the connection between virulence factors and beta-lactam antibiotic resistance were discussed.
出处
《动物医学进展》
CSCD
北大核心
2014年第9期106-109,共4页
Progress In Veterinary Medicine
基金
国家自然科学基金项目(31201954)
