虫草多糖药理活性及机制研究的进展

Research Progress of Pharmacological Activities and Mechanisms of Cordyceps Polysaccharide

糖生物学的研究进展使多糖成为生命科学研究的热点。传统中药冬虫夏草以有效成分复杂、药理活性广泛倍受关注。研究技术的发展更促进了国内外学者对虫草菌物二级成分的探索,虫草多糖作为其最主要的活性成分,在糖生物学时代显示出潜在而突出的研究价值。药理研究证实,其具有调节免疫、抗肿瘤、肝肾保护、抗氧化等生物活性。该文通过对虫草多糖药理活性及机制的文献总结,为中药多糖活性研究提供理论基础。

Polysaccharide is becoming a hot spot of life science research with the progress of glycobiology. Traditional Chinese medicine cordyceps sinensis has attracted wide attention because of its complex compo- nents and diverse pharmacological activities. And the development of research technology promotes more exploration on the secondary elements of cordyceps sinensis. Cordyceps polysaccharide as its main active ingredient, shows potential and outstanding research value in the era of glycobiology. Pharmacological studies have confirmed its regulating immunity, antl-tumor, liver and kidney protection, anti-oxidation and other biological activities. Through summarizing the literatures of cordyceps polysaeeharide pharmacological activi- ties and mechanisms ,here is to provide certain theoretical basis for the research of polysaccharides activity in traditional Chinese medicine.