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泛素特异性肽酶22基因与肿瘤发展和预后的研究进展 被引量：1

Research progress of relationship between ubiquitin specific peptidase 22 gene and process and prognosis of cancer
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摘要 泛素特异性肽酶22（ubiquitin—specificprocessingpeptidase22，USP22）是一种新型的去泛素化酶家族基因，是hSAGA复合物的亚单位。越来越多的实验研究结果证明泛素特异性肽酶22（USP22）是癌干细胞标记物中的一种，在肿瘤形成及发展的病理过程中扮演关键的角色，并与不良预后有着密切的关系。 Ubiquitin specific peptidase 22 （ubiquitin-specific processing peptidase 22, USP22）, a novel deubiquitinating enzyme, is one subunit of hSAGA complexes. More and more studies have proved that USP22 is one of a small set of cancer stem cell markers, which plays a key role in the pathological process of various malignant tumors＇ formation and development and is closely associated with poor prognosis.
作者 庄雅靖 喻芳 周同冲
机构地区 广州医科大学附属肿瘤医院
出处 《国际医药卫生导报》 2014年第17期2627-2631,共5页 International Medicine and Health Guidance News
基金 广州医科大学附属肿瘤医院重大专项（2011-gy-06） 广州医科大学青年项目（2012A15）
关键词 USP22 癌干细胞标记物 肿瘤形成及发展 不良预后 Ubiquitin specific peptidase 22 Cancer stem cell marker Tumors＇ formation anddevelopment Poor prognosis
分类号 R730.2 [医药卫生—肿瘤]
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参考文献27

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国际医药卫生导报
2014年 第17期

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