基于氨基偶氮苯的光和pH响应聚[(三甲基丙烯酸乙酯胺)_8-(4-氨基-4'-甲基丙烯酰胺基偶氮苯)_1](T_8A_1)的合成与表征

Synthesis and Characterization of Novel Photo-and pH-Responsive Poly[( triethylacrylateamine)_8-( triethylacrylateamine)_1]( T_8A_1)

以对硝基苯胺为原料,经过偶联、还原和酰化反应,合成了4-氨基-4'-甲基丙烯酰胺基偶氮苯(AMAB);将三乙醇胺和甲基丙烯酰氯反应制得水溶性的十字交联剂三甲基丙烯酸乙酯胺(TMAEA);将AMAB和TMAEA进行自由基沉淀聚合反应,制得基于氨基偶氮苯的新型纳米级聚合物——聚[(三甲基丙烯酸乙酯胺)8-(4-氨基-4'-甲基丙烯酰胺基偶氮苯)1](T8A1),并用紫外-可见光谱(UV-Vis)、红外光谱(IR)、热失重(TG)和扫描电子显微镜(SEM)对T8A1进行了表征.结果表明,T8A1在水中具有光和pH双重响应性能,弥补了传统的偶氮苯类材料仅能在有机溶剂中具有响应的缺陷,具有广阔的仿生应用前景.

A photo-responsive functional monomer 4-amino-4′-methylacrylamide azobenzene （ AMAB ） was synthesized by coupling, reduction, and acylation reaction with 4-nitroaniline as the starting material. A water-soluble cross-linker triethylacrylateamine（ TMAEA） was synthesized by acylation reaction with triethano-lamine and methacrylic chloride and confirmed by nuclear magnetic resonance （ NMR ） . A novel photo- and pH-responsive polymer： poly [ （ triethylacrylateamine ） 8-（ triethylacrylateamine ） 1 ] （ T8 A1 ） was successfully prepared by radical polymerization with AMAB and TMAEA using azo bisisobutyronitrile（ AIBN） as the initia-tor. The T8 A1 was characterized by thermeagravimetry analysis（ TGA） , infrared（ IR） , scanning electromic mi-croscoy（ SEM） , and ultravidet visible（ UV-Vis） . The T8 A1 exhibited both photo- and pH-response in water, which overcame the shortcoming of conventional azobenzene derivatives that they could only work in organic solvents and lose efficiency in aqueous media. These results made T8 A1 amenable for applications in multi-stimuli responsive systems and biotechnology.