肾上腺素联合布地奈德雾化吸入治疗小儿急性感染性喉炎的临床研究

Clinical research of Epinephrine hydrochloride combined with Budesonide for atomization inhalation in treatment of children's acute infectious laryngitis

目的:探讨盐酸肾上腺素联合布地奈德雾化吸入治疗小儿急性感染性喉炎的临床效果。方法:将58例急性感染性喉炎患儿按不同治疗方法分为实验组(30例,常规治疗+盐酸肾上腺素联合布地奈德雾化吸入)和对照组(28例,常规治疗+静脉滴注地塞米松),对两组患儿的治疗效果进行综合比较。结果:(1)治疗12h后,实验组患儿的治疗总有效率为96.67%,明显高于对照组(75.00%)(P<0.05);(2)实验组患儿声嘶、呼吸困难、喉鸣音等症状体征消失时间明显少于对照组(P<0.01)。结论:盐酸肾上腺素联合布地奈德雾化吸入治疗小儿急性感染性喉炎效果显著,值得临床推广应用。

Objective：To investigate clinical effects of Epinephrine hydrochloride combined with Budesonide for atomization in-halation in treatment of children＇s acute infectious laryngitis. Methods：58 children with acute infectious laryngitis were divided into ex-perimental group （30 cases, conventional therapy ＋ Epinephrine hydrochloride and Budesonide for atomization inhalation） and control group （28 cases, conventional therapy ＋ Dexamethasone through intravenous drip）. The efficacies of the two groups were compared. Results： （1） 12h after the treatment, the total effective rate of experimental group （96. 67% ） was significantly higher than that of control group （75. 00% ） （P〈0. 05）. （2）The disappearance time of hoarseness, dyspnea, and throat beep in experimental group was less than that in control group （P〈0. 01）. Conclusions： There are significant effects of Epinephrine hydrochloride combined with Budesonide for atomization inhalation in the treatment of children＇s acute infectious laryngitis, which is worthy of clinical promotion and application.