银合欢豆荚中的酚类化学成分

Phenolic Compounds from Pods of Leucanea leucocephala

为探讨银合欢(Leucaena leucocephala)的化学成分,从银合欢豆荚乙醇提取物中分离得到7个酚类化合物,经过波谱分析,鉴定为原儿茶酸乙酯(1)、丁香酸(2)、3-羟基-1-(3-甲氧基-4-羟基苯基)丙烷-1-酮(3)、咖啡酸甲酯(4)、(Z)-对香豆醛(5)、3-甲氧基-4-羟苯丙烷-7,8,9-三醇(6)、愈创木基甘油-8-O-4′-芥子醇醚(7)。所有化合物均为首次从该植物中分离得到。化合物1对大肠杆菌和鼠伤沙门氏菌有一定的抑制活性。

In order to understand the chemical constituents of Leucanea leucocephala, seven phenolic compounds were isolated from the ethanol extract of L. leucocephala pods. On the basis of spectral data, they were identiifed as ethyl protocatechuate (1), syringic acid (2), 3-hydroxy-1-(4-hydroxy-3-methoxyphenyl)propan-1-one (3), caffeic acid methyl ester (4), (Z)-p-coumaric aldehyde (5), 3-methoxy-4-hydroxy-phenylpropane-7,8,9-trio1 (6), and guaiacylglycerol-8-O-4′-(sinapyl alcohol) ether (7). All the compounds were obtained from L. leucocephala for the first time. Compound 1 showed in vitro antibacterial activity against Escherichia coli and Salmonella typhimurium strains.