摘要
目的探讨单、多相位动脉自旋标记(ASL)灌注技术的优缺点以及在脑卒中患者中的临床应用价值。方法对31例脑卒中患者行常规MRI、扩散加权成像(DWI)和单、多相位ASL检查。观察2种方法的灌注特点,包括低灌注、正常灌注、延迟灌注、高灌注等,比较2种方法各自的优势。分别在DWI、ASL上确定病变的范围,比较两者之间的关系。结果31例患者中,23例单、多相位ASL灌注结果完全一致(低灌注14例,低灌注伴局部高信号3例,高灌注4例,正常灌注2例),8例灌注结果不完全一致,(2例单相位显示低灌注,多相位为延迟灌注;6例单相位显示低灌注,多相位为低灌注伴局部高信号)。30例脑卒中患者中,DWI与ASL对同一病例相同病变显示面积大小:SDWI<SASL,n=13;SDWI≈SASL,n=16;DWI阳性而ASL阴性,n=2。结论ASL能基本反映脑梗死区的血流灌注情况,多相位ASL在显示脑卒中延迟灌注、局部高信号(提示侧枝循环)方面比单相位ASL更具优势,单相位ASL图像信噪比相对较高。
Objective To investigate the single, multi-phase ASL perfusion technique,analyze the application value in patients with cerebral ischemic infraction. Methods Routine MRI scanning、DWI、and single, multi-phase ASL were performed on 31 patients with acute ischemic stroke. Perfusion deficits, normal perfusion, delayed perfusion and hyperfusion were observed, compared advantages of 2 methods. Areas of infarction measured on DWI and ASL were compared.Results The two techniques demonstrated agreement in 23 of 31 patients （hypoperfusion, n=14; low perfusion with local high signal, n=3;normal perfusion, n=2; hyperfusion, n=4）. 8 cases were not completely consistent, （8 cases of single-phase ASL showed low perfusion, 2 cases of multi-phase ASL showed delayed perfusion; 6 cases showed low perfusion with local high signal）.The size of the same lesions in the same patient showed by DWI and ASL appeared： SDWI〈SASL, n=13; SDWI≈SASL, n=16; 2 cases showed positive results on DWI and negative on ASL.Conclusion ASL can reflect the blood perfusion of cerebral infarction, multi-phase ASL in displaying delayed perfusion, local high signal （presented collateral circulation） has more advantages than single-phase ASL, single phase ASL image better SNR.
出处
《中国CT和MRI杂志》
2014年第6期4-7,共4页
Chinese Journal of CT and MRI
