摘要
目的对补益强心片治疗充血性心力衰竭进行临床疗效评价。方法采用双盲双模拟、平行单中心、扩大多中心和开放单中心试验方法,临床选择420例(300︰120)符合充血性心力衰竭(气阴两虚兼血瘀水停证)诊断标准的患者,分别服用补益强心片及地高辛片。结果中医证候疗效:试验组与对照组比较差异有统计学意义(P<0.05);两组患者的射血分数及每搏输出量较治疗前皆有增加,前后比较差异有统计学意义(P<0.05);治疗前后肝脾肿大、水肿、啰音、心率比较差异无统计学意义(P>0.05);治疗前后血压比较,差异有统计学意义(P<0.05)。结论补益强心片治疗充血性心力衰竭的疗效与西药相似。临床试验中未见不良反应及毒副作用。
ObjectiveToevaluate clinical efficacy and adverse reaction of Buyi Qiangxin tablets.Methods Double-blind ＆ dummy, paralleled single center, expand multi-center, and informed single center. 420 CHF patients （300︰120） were chosen to take Buyi Qiangxin tablets and digoxin tablets respectively.Results Compared experimental group and the control group,P〈0.05. The experimental group is better than the control group. All patients＇ ejection fraction and stroke volume increased（P〈0.05）. There is no difference between two groups, before and after treatment, in aspect of hepatosplenomegaly, oedematous rale, heart rate （P〉0.05）,and significant difference in blood pressure（P〈0.05）.ConclusionBuyi Qiangxin tablets has equal clinical curative effect for CHF compared with western medicine. No adverse reactions and side effects in clinical trials.
出处
《中国医药科学》
2014年第16期19-22,共4页
China Medicine And Pharmacy
基金
国家中医药管理局科研基金课题(95A2112)
