参芪花粉片联合β受体阻滞剂治疗血管迷走性晕厥疗效观察

Clinical observation of Shenqi pollen plates combined with beta adrenergic antagonists in treatment of vasovagal syncope

目的探讨参芪花粉片联合β受体阻滞剂治疗血管迷走性晕厥与单用β受体阻滞剂疗效的比较。方法将96例确诊为血管迷走性晕厥的患者随机分为2组,对照组患者服用琥珀酸美托洛尔缓释片,47.5mg/次,1次/d,实验组加用参芪花粉片3.75g/次,2次/d。治疗前及治疗3个月后分别进行直立倾斜试验,同时观察患者晕厥复发情况。结果实验组有效率为85.4%,对照组有效率为70.8%(P<0.05)。两组治疗前后平均血压差值均数比较治疗组小于对照组(P<0.05),平均心率比较治疗组小于对照组(P>0.05)。结论参芪花粉片联合β受体阻滞剂治疗血管迷走性晕厥的疗效明显优于单用β受体阻滞剂,且有稳定血压作用,药物安全性也更高。

Objective To observe the clinical effect of Shenqi pollen plates combined with beta adrenergic antagonists in treatment of vasovagal syncope.Methods 96 vasovagal syncope patients in our hospital were randomly divided into two groups, which were treatment group and control group. Two groups were given metoprolol succinate extended release tablets 47.5mg orally, once a day, additionally, treatment group was given Shenqi pollen plates 3.75g orally, twice a day, and were followed up for 3 months. Head-up tilt testing was performed before treatment and reviewed three months later, moreover, recording the recurrence of syncope.Results The therapeutic efficiency ratio of treatment group was 85.4%,while the control group was 70.8%（P〈0.05）.Before and after treatment, means of blood pressure difference in treatment group was less than control group（P〈0.05）, means of heart rate difference in treatment group was less than control group（P〉0.05）.ConclusionThe therapeutic efficiency of Shenqi pollen plates combined with beta adrenergic antagonists is better than taking beta adrenergic antagonists alone, blood pressure can be more stable, safety can be higher.