硅油乳化相关因素临床分析

Clinical analysis of the silicone oil emulsification related factors

目的 分析一定时期硅油填充术后病人乳化集中趋势及其发生率,探讨硅油乳化的相关因素.方法 临床病例回顾性分析研究.选择2007年1月至2012年1月在青岛大学医学院附属医院眼科行硅油填充治疗的患者为研究对象,并按原始疾病、有无晶状体、硅油填充时间、硅油填充次数归类,统计硅油乳化发生情况.结果 符合标准者807只眼,其中硅油乳化108只眼（13.4％）.硅油乳化发生情况：根据不同原始疾病比较,差异有统计学意义（x2=8.11,P=0.04）;根据有无晶状体比较,差异有统计学意义（x2=25.61,P＜0.01）;根据硅油填充时间比较,差异有统计学意义（x2=10.34,P=0.006）;根据硅油填充次数比较,差异无统计学意义（r=1.18,P＞0.05）.结论 硅油填充术后硅油乳化的原因与原始疾病、有无晶状体、硅油填充时间有一定关系,与硅油填充次数无关;应适时取出硅油,以减少硅油乳化及其并发症的发生.

Objective To analyze the central tendency and the emulsification rate of silicone oil filling in postoperative patients,to explore the related factors of silicone oil emulsification.Methods Clinical cases were retrospectively studied and analyzed.The patients who treated by silicone oil in ophthalmology of Qingdao university medical school affiliated hospital between January 2007 and January 2012 were selected.The cases of emulsification in the course of removing silicone oil were summarized.The rate of them by initial diseases,presence of crystal,filling time and filling times was analyzed.Results The eyes according with criterion were 807,emulsification was performed on 108 eyes：In different initial diseases,the difference had statistics significance （P =0.04） above the x2 test; In presence of crystal,the difference also had statistics significance （P 〈0.001）; In different time,it had statistics significance too （P =0.006）; In different times,there was no statistically significant difference （P 〉0.05）.Conclusions The silicone oil emulsification is related with initial diseases,presence of crystal and silicone oil filling time,but it has nothing to do with silicone oil filling times.Silicone oil should be removed timely to reduce the happening of silicone oil emulsification and complications of silicone oil emulsification.