焦虑症服用丁螺环酮辅以经颅磁刺激的临床研究

Clinical research on anxiety treated with Buspirone supplemented with transcranial magnetic stimulation

目的:研究焦虑症服用丁螺环酮辅以经颅磁刺激的临床疗效。方法:选取我院焦虑症患者随机分为临床组和参照组各57人。参照组应用丁螺环酮进行治疗,临床组在其基础上实施经颅磁刺激治疗。治疗结束后,比照两组临床疗效、焦虑自评量表及抑郁自评量表的治疗前后变化情况。同时随访两组汉密尔顿焦虑量表评分的特定节点改善情况。结果:临床组总有效率为91.23%,显著高于参照组的71.93%。两组治疗前SAS及SDS评分无显著差异,治疗后均改善显著,而临床组其改善幅度显著优于参照组。两组治疗前哈密尔顿焦虑评分比照无显著差异,治疗后2个月及治疗后半年均比照治疗前显著改善,而临床组其改善幅度显著优于参照组。结论:焦虑症服用丁螺环酮辅以经颅磁刺激临床疗效确切。

Objective： To study the clinical effect of Buspirone supplemented with transcranial magnetic stimulation on anxiety.Methods： Patients with anxiety disorder in our hospital were randomly divided into a clinical group and a control group, 57 cases in eachgroup. Patients in the control group were treated with Buspirone, while patients in the clinical group were treated with transcranialmagnetic stimulation based on treatment of Buspirone. After treatment, the clinical efficacy and the changes of self rating anxiety scale andself-rating depressive scale were compared. At the same time, specific node of two groups of Hamilton Anxiety Scale score improvementwas followed up. Results： The total effective rate of the clinical group was 91.23%, significantly higher than that of the control group71.93%. The scores of SAS and SDS before treatment had no significant difference. After treatment, it obviously improved, and the clinicalgroup was better than that of the control group. There was no significant difference on Hamilton Anxiety Scale score. Compared 2 monthsand 6 months after treatment, it significantly improved and the clinical group better than the control group. Conclusion： Buspironesupplemented with transcranial magnetic stimulation has an accurate effect on anxiety.