襄阳市感染性腹泻病原菌调查

Investigation on infectious diarrhea pathogens in Xiangyang City

目的了解襄阳市感染性腹泻的病原学及流行病学特征,为感染性腹泻的有效控制提供科学依据。方法对襄阳市第一人民医院2013年1月—12月就诊的273例门诊和住院腹泻患者的粪便进行病原学和病毒学检测,并对病原菌的病原谱构成、时间分布、人群分布进行统计学分析。结果从273份粪便标本共检出病原体165份,检出率为60.44%,检出肠道致病菌5株,检出率0.18%;检出肠道病毒160份,检出率为58.61%。肠道腺病毒检出率较高;轮状病毒感染有明显季节特征,秋冬季为发病高峰;诺如病毒感染临床症状表现较重。2岁以下年龄组感染率显著高于其他年龄组。结论襄阳市感染性腹泻以病毒性腹泻为主,其中肠道腺病毒和轮状病毒是主要病原,细菌性引起的感染性腹泻检出率较低。应加强对病毒性腹泻,尤其是婴幼儿病毒性腹泻的监测。

Objective To understand the pathogenic and epidemiological characteristics of infectious diarrhea in Xiangyang City, so as to provide the evidence for effective control. Methods The stool samples of 237 cases of diarrhea were examined for the etiology in Xiangyang City from January to December, 2013, and the results were analyzed statistically. Results The pathogens were detected in 165 from 273 stool samples and the positive rate was 60.44%. Five strains of enteric pathogens were detected and the detection rate was 0.18 % ; 160 cases of enterovirus were detected and the detection rate was 58.61%, which showed the higher detection rate of enteric adenovirus. Rotavirus infection had obvious seasonal characteristics, which peaked in autumn and winter. The symptoms of norovirus infection were heavy. The infection rate of the under-2-year age group was higher than that of other age groups. Conclusions The main pathogen of infectious diarrhea is virus including the intestinal gland virus and rotavirus in Xiangyang City. We should strengthen the monitoring of viral diarrhea, especially the viral diarrhea in infants.