冠心病患者白蛋白尿和血清尿酸水平的关系研究

Analyze Relationship Between Albuminuria and Serum Uric Acid Levels of Coronary Heart Disease Patients

目的 探讨冠心病患者白蛋白尿和血清尿酸水平的关系.方法 选取2010年5月～ 2013年5月该院收治的90例冠心病患者为研究对象,测定患者入院次日清晨血清尿酸（UA）、尿素氮（BUN）、血清肌酐（Scr）、甘油三酯（TG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、空腹血糖（FPG）水平,以及24小时白蛋白尿（mALB）.其中白蛋白尿＜30 mg/24 h患者记为阴性组,＞30 mg/24 h患者记为阳性组.结果 阳性组患者血清尿酸、甘油三酯、低密度脂蛋白胆固醇均高于阴性组,高密度脂蛋白胆固醇低于阴性组,两组对比差异明显,具有统计学意义（P＜0.05）.结论 冠心病患者白蛋白尿和血清尿酸水平存在相关性,血清尿酸是引起冠心病患者出现白蛋白尿的危险因素,临床应给予重视.

Objective Research relationship between albuminuria and serum uric acid levels in coronary heart disease patients. Methods From May 2010 to May 2013, selected 90 cases of coronary heart disease patients for this study. After admitting to hospital the next morning, serum uric acid （UA） , urea nitrogen （ BUN）, serum creatinine （Scr） , glycerol three ester （TG）, total cholesterol （ TC）, low- density lipoprotein cholesterol （LDL-C）, high density lipoprotein cholesterol （HDL-C）, fasting plasma glucose （FPG） levels, and 24 hours albuminuria （mALB） were measured, albuminuria of patients 〈 30 mg/24 h recorded as negative, 〉 30 mg/24 h recorded as positive group. Results In positive group serum uric acid,triglycerides,low-density lipoprotein cholesterol were higher than the negative group, highdensity lipoprotein cholesterol was lower than negative group, there was significant differences between two groups （P 〈0.05）. Conclusion There was correlations between albuminuria and serum uric acid level correlation in patients with coronary artery disease. Serum uris acid is risk factor that caused albuminutia in coronary heart disease patients, clinical attention should be paid.