针刺辅助生殖功能的国外研究进展

Development of Researches on Acupuncture-assisted Fertilization Outside of China

计算机检索Ovid平台联机的Medline、Maternity and Infant Care数据库及单独检索Medline(Pubmed)数据库中2003年1月-2013年5月国外英文杂志发表的针刺在辅助生殖领域应用的文献。分析发现目前对针刺应用于辅助生殖领域是否具有临床作用争议较大,虽然阳性结果的随机对照临床试验研究占优势,认为针刺可以改善胚胎移植临床结局,但现有的系统评价以阴性结论者居多,认为尚缺乏针刺有助于辅助生殖的证据支持,还需进一步设计严谨合理的相关研究为针刺在辅助生殖领域的应用提供证据。

Increasing evidence shows that acupuncture therapy may have a role in promoting fertilization. Authors of the present paper collected the related articles in English published from January 2003 to May 2013 in databases of Ovid Medline, Maternity and Infant Care and Medline（Pubmed）, and made an analysis. Results of many randomized controlled clinical trials （RCT） indicated that acupuncture intervention had a positive role in raising pregnancy rate, fetus surviving rate of the transplanted embry- o, and increasing the neuropeptide Y content in the ollicular fluid in patients experiencing embryo transplantation, and in raising survival rate of zygote, conception rate of embryo transplantation, and in improving azoospermia in patients undergoing in vitro fertilization. But many systematic reviews and Meta-analysis did not support the above-mentioned conclusion of acupuncture therapy about promoting fertilization. The authors hold that despite of dominated positive outcomes of ROT for acupuncture-assisted fertilization, further well designed ROT are still warranted for providing further definite and convincing evidence.