慢性持续性低度炎症与运动、健康和疾病的研究进展

Research Progress on the Relationships of Chronic Low-Grade Inflammation,Exercise,Health and Disease

背景:研究表明慢性低度炎症在多数非传染性疾病的发病中起着关键作用,2014年ACSM年会把炎症在运动、健康和疾病中的作用作为热点专题。目的:探讨运动、营养、衰老、脂肪和骨骼肌与慢性炎症的关联。方法:分析归纳目前本方向年会的热点研究结果及进展。结果与结论:1)衰老及不良生活方式是慢性低度炎症的重要致炎因素;2)急性运动可促进炎症因子的产生,规律运动可以减低炎性标志物;3)运动能降低骨骼肌慢性炎症;4)运动能降低脂肪组织的慢性炎症;5)规律运动是降低年龄相关的慢性炎症反应的一种手段;6)营养补给对急性运动诱导的炎性反应的干预效果有待进一步研究。研究表明运动的抗炎作用可能是其降低慢性低度炎性疾病发生的重要机制。

Background： Studies have shown that chronic low-grade inflammation plays a pivotal role in the most common non-contagious diseases （CNCDs）. In the 2014 ACSM＇s annual meeting, inflammation＇s function in exercise, health and disease is a hot seminar. By the methods of analyzing and summarizing the research results and progress presented in this annual meeting, this paper discussed the correlation between exercise, nutrition, ageing, fat, skeletal muscle and inflammation. Conclusions ： 1） Aging and bad lifestyle are the key pro-inflammation factors. 2） Acute exercise will motivate inflammatory cytokines production; regular exercise can reduce chronic low-grade inflammation markers. 3 ） Exercise can reduce chronic inflammation of skeletal muscle. 4） Exercise can reduce chronic inflammation in fatty tissue. 5 ） Regular exercise is a way to reduce aging-related chronic inflammation. 6） The effect of nutrition supplement on inflammation induced by acute exercise needs further study. These results showed that exercise＇s anti-inflammatory effect may be the mechanism of that exercise can reduce chronic low-grade inflammatory diseases.