DUV 光子创可贴联合康复新液治疗口腔黏膜炎的效果

Effect of DUV photon Band-Aid combining with new Kangfu solution on the treatment of oral mucositis

目的：探讨DUV光子创可贴联合康复新液治疗口腔黏膜炎的效果。方法选择小儿血液科恶性肿瘤疾病患儿化疗后并发口腔黏膜炎患儿120例。将120例患儿按照随机数字表发分为对照组和试验组各60例。对照组：使用康复新液、1．4％碳酸氢钠溶液、甲硝唑溶液及复方硼砂溶液4种，每种溶液3次/d，4种溶液交替含漱，康复新液含漱后口服。试验组在使用原有的漱口液康复新液的基础上，联合DUV光子创可贴进行治疗。康复新液3次/d含漱后口服；DUV光子创可贴2次/d，1次120 s，贴近患处进行照射。结果两组患儿口腔黏膜炎在不同部位的愈合时间比较，试验组患儿面颊、腭、齿龈、舌、唇愈合时间分别为（6．87±2．12），（8．03±1．73），（6．42±1．46），（6．24±1．45），（5．00±1．19）d，均优于对照组的（8．28±2．65），（9．46±2．05），（8．13±1．45），（7．38±1．44），（6．20±1．86）d，差异有统计学意义（t值分别为2．64，2．94，3．44，2．82，2．25；P＜0．05）。试验组患儿Ⅰ～Ⅱ度愈合时间为（5．00±1．24）d，Ⅲ～Ⅳ度愈合时间为（9．76±1．49）d，均优于对照组的（5．87±1．42），（11．14±2．05）d，差异有统计学意义（t值分别为2．78，2．72；P＜0．05）。结论康复新液与DUV光子创可贴联合应用于口腔黏膜炎，可产生协同作用，明显缩短溃疡愈合时间。

Objective The study aimed to explore the effects of DUV photon Band-Aid combining with new Kangfu solution on the treatment of oral mucositis .Methods A total of 120 children with malignant tumor who had got oral mucositis after chemotherapy were included in the study .They were randomly and evenly divided into two groups .The control group was given new Kangfu solution , 1.4%sodium bicarbonate solution , metronidazole solution and compound borax solution .Each solution was given three times a day and alternately gargled, then new Kangfu solution was contained and orally took in .Based on the new Kangfu solution , DUV photon Band-Aid was added to the experimental group nearby the oral mucositis twice a day for 120 seconds each time.Results The healing time of oral mucositis in different parts , such as cheek, palate, gingival, tongue and lip were （6.87 ±2.12）, （8.03 ±1.73）, （6.42 ±1.46）, （6.24 ±1.45） and （5.00 ±1.19） days in the experimental group.Those healing time in the control group were （8.28 ±2.65）, （9.46 ±2.05）, （8.13 ± 1.45）, （7.38 ±1.44） and （6.20 ±1.86）.The differences were statistically significant （t=2.64, 2.94, 3.44, 2.82, 2.25, respectively;P〈0.05）.In the experimental group, the healing time of ⅠtoⅡdegrees andⅢtoⅣdegrees were （5.00 ±1.24） and （9.76 ±1.49） days, which were significantly better than （5.87 ± 1.42） and （11.14 ±2.05） days （t =2.78, 2.72, respectively; P〈0.05）.Conclusions Combine DUV photon Band-Aid with new Kangfu solution can produce synergistic effect and obviously shorten the healing time .