呼吸内科下呼吸道感染病原菌及耐药分析

Respiratory Medicine,lower respiratory tract infection pathogens and drug analysis

目的研究呼吸内科下呼吸道感染的患者病原菌以及耐药性的分析。方法选取2008年1月至2012年1月3074例下呼吸道感染患者的痰菌进行培养,同时进行药敏试验,对所得结果进行分析。结果通过对本文所选的3074份痰标本进行检验分析,其中有1344份培养为阳性,阳性率为43.72%;阳性标本中有1564例菌株,其中1092株为革兰阴性球菌,占69.82%,主要的菌属为大肠埃希菌、铜绿假单胞菌、克雷伯菌属以及不动杆菌属;314株为革兰阳性球菌,占20.08%,主要菌属为金黄色葡萄球菌、肺炎链球菌以及表皮葡萄球菌;158株为真菌,占10.10%,主要为白色假丝酵母菌。结论呼吸内科住院患者出现下呼吸道感染主要致病菌为革兰阴性杆菌感染,病原菌对药物的敏感性出现了不同的改变,临床上应合理选择抗菌药物,以防病原菌出现耐药性。

Objective To study the respiratory medicine in patients with lower respiratory tract infection pathogens and drug resistance analysis. Method The hospital on January 2008-January 2012 between the Department of Respiratory Medicine 3074 cases of hospitalization in patients with lower respiratory tract infection were cultured sputum, and susceptibility testing, the obtained results were analyzed. Result By 3074 article selected sputum samples for examination and analysis, including 1344 were culture positive, the positive rate was 43. 72%; positive strain was detected in 1564 cases, of which 1092 Gram-negative bacteria, accounting for 69. 82% the main genus of Escherichia coli, Pseudomonas aeruginosa, Klebsiella and Acinetobacter spp; 314 Gram-positive cocci, accounting 20. 08%,the main species of Staphylococcus aureus, Streptococcus pneumoniae and Staphylococcus epidermidis;158 as fungi, accounting for 10. 10%, mainly Candida albicans. Conclusion Respiratory Medicine hospitalized patients with lower respiratory tract infection pathogens were mainly Gram-negative bacteria infection, pathogen sensitivity to drugs appeared different changes, clinicians shadow reasonable choice of antimicrobial drugs to passionately pathogen emergence of drug resistance.