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右美托咪定对直肠癌术后镇痛效果的影响 被引量:2

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摘要 目的:观察右美托咪定对直肠癌术后镇痛效果的影响。方法:选择择期直肠癌手术患者60例,随机分为观察组和对照组,观察组麻醉诱导前给予右美托咪定0.5μg/kg,继以0.2μg/(kg.h)持续输注至术毕;对照组给予等量生理盐水。术后予以舒芬太尼自控静脉镇痛(PCIA),观察术后不同时点视觉模拟评分(VAS)、痛阈值、皮质醇浓度及舒芬太尼用量,比较两组指标差异。结果:观察组VAS评分、皮质醇浓度和舒芬太尼用量低于对照组,痛阈值无明显差异。结论:预注0.5μg/kg右美托咪定并术中输注0.2μg/(kg.h),可以增加直肠癌术后舒芬太尼的镇痛效果。
作者 刘会林
机构地区 唐山市开平医院
出处 《贵阳中医学院学报》 2014年第5期69-70,共2页 Journal of Guiyang University of Chinese Medicine
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  • 1M.S.Angst,W.Koppert,I.Pahl,D.J.et al.Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal,Pain106 (2003) 49-57.
  • 2Wu CL,Raja SN.Treatment of acute postoperative pain.Lancet,2011,377:2215-2225.
  • 3Ralph Gertler,Cleighton Brown,Donald,et al.medetomidine:a novel sedative-analgesic agent.Bumc Proceedings 2001:1 4:13-2 1.
  • 4T.J.Ebert,J.E.Hall,J.A.Barney,et al.The effects of increasing plasma concentrations of medetomidine in humans,Anesthesiology 93 (2000) 382-394.
  • 5Belgrde M,Hall S.medetomidine infusion for the management of opioid-induced hyperalgesia[J].Pain Med,2010,11 (12):1819-1826.
  • 6沈健,陈家伟,缪长虹.不同剂量右旋美托咪定对术后谵妄和镇痛的影响[J].中国临床医学,2013,20(3):340-342. 被引量:12
  • 7KLAMT J G,ANDRADE VICENTE W V,GARCIA L V,et al.Effects of medetomide-fentanyl infusion on blood Pressure and heart rate during cardiac surgery in children[J].Anesthesiol Res Pract,2010,19(8):311-316.

二级参考文献5

  • 1Cole MG. Delirium in elderly patients[J]. Am J Geriatr Psy chiatry,2004,12(1) : 7-21.
  • 2Shukry M, Clyde MC, Kalariekal PI, et al. Does dexmedeto- midine prevent emergence delirium in children after sevoflurane-based general anesthesia [Jl. Paediatr Anaesth, 2005,15(12): 1098-1104.
  • 3Maldonado JR, Wysong A, Van der Starre PJ, et al. Dexme detomidine and the reduction of postoperative delirium after cardiac surgery[J]. Psychosomaties, 2009, 50(3):206-217.
  • 4Ohtani N, Yasui Y, Watanabe D, et al. Perioperative infusion of dexmedetomidine at a high dose reduces postoperative anal gesic requirements= a randomized control trial[J]. J Anesth, 2011, 25(6) : 872-876.
  • 5Nelson LE, Lu J, Guo TZ, et al. The (x2 Adrenoceptor ago- nist dexm edetomidine converges on an endogenous sleep pro moting pathway to exertits sedative ef[ects[J]. Anesthesiolo gy, 2003, 98(2): 428-436.

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