尿碘评价哺乳期妇女碘营养的稳定性分析

Stability analysis of using urinary iodine concentration to evaluate lactating women's iodine nutrition

目的分析哺乳期妇女尿碘浓度的稳定性,评价其碘营养。方法 2012年4~5月选择碘盐覆盖良好的甘肃省临夏县尹集乡,连续跟踪采集3次自然饮食和生活状态条件下哺乳期妇女间隔10 d随机1次性尿样。采用过硫酸铵消化-砷铈催化分光光度方法（WS/T 107-2006）检测尿碘含量。结果 3次尿碘中位数分别为188.13μg/L、185.0μg/L和172.9μg/L,尿碘中位数和频数构成无显著性差异（P〉0.05）;同一个体3次尿碘在同一水平的比例占9.2%（29/184）,两次尿碘浓度在同一水平的比例均〈20%;以第1次检测结果为基准,第2次尿碘浓度在〈150μg/L、150~250μg/L、250~500μg/L和〉500μg/L同一水平的符合率分别为53.2%、36.5%、31.3%和14.3%,第3次尿碘在〈150μg/L、150~250μg/L、250~500μg/L和〉500μg/L四个水平的符合率分别为44.2%、23.1%、16.7%和0.0%。结论在自然饮食和生活状态下,同一个体不同时间尿碘浓度的符合率低,一致性差,但总体3次尿碘处于一个稳定的状态,因此一次性尿碘浓度不能对个体碘营养作出正确评价,但能够反映群体的碘营养水平。根据尿碘浓度判定,在目前碘盐落实的情况下,调查点的哺乳期妇女碘营养适宜。

Objective Analysis of lactating women urinary iodine concentration stability and evaluation the iodine nutrition. Methods Between April and May in 2012, continuously collected lactating women random urine interval 10 days three times in natural diet and living conditions in Yinji town of Linxia county, Gansu province. The results of the three median of urinary iodine were 188.13 μg,/L, 185 μg/L and 172.9μg/L, the median of urinary iodine and frequency bad no significant differences（ P 〉0. 05） ; Three times urinary iodine of the same individual was 9.2% at the same level （ 29/184 ）, twice urinary iodine at the same level was 〈20%; As the first test results for reference, the second urinary iodine consistent rate of 〈150 μg/L, 150 -250 μg/L, 250-500 μg/L and 〉500 μg/L were 53.2%, 36.5%, 31.3% and 14.3%, and the third were 44.2%, 23.1%, 16.7% and 0% respectively. Conclusion In the natural diet and living conditions, the coincidence rate of the same individual urinary io- dine concentration was low at different time, and consistency was poor, but the three times urine iodine level of population was at a stable state, therefore, urinary iodine concentration can not evaluate individual iodine nutrition correctly, but can reflect the group ＂s iodine nutrition level. According to the urinary iodine concentration, the lactating women iodine nutrition was suitable in the current implementation situation of iodized salt.