急性胆囊炎患者感染的危险因素分析

Analysis of risk factors for infections following acute cholecystitis

目的探讨急性胆囊炎发生感染的危险因素并进行相关性分析,以降低急性胆囊炎感染的发生率。方法回顾性分析2010年12月-2013年1月收治的246例急性胆囊炎患者临床资料,观察患者感染情况,并收集患者入院前相关资料分别进行单因素和多因素logistic回归分析。结果 246例患者中有54例发生感染,感染率21.95%;单因素分析显示,年龄、性别、饮食习惯、糖尿病、肝硬化、白细胞计数、胆囊周围积液、胆囊结石等是引起急性胆囊炎发生感染的危险因素(P<0.05);进一步行多因素logistic回归分析显示,患者的年龄、性别、饮食习惯、糖尿病、白细胞计数和胆囊结石是导致感染的独立危险因素。结论影响急性胆囊炎患者发生感染的危险因素较多,对老年女性且患有糖尿病患者需要早期进行正确的诊断、早期手术,减少感染的发生。

OBJECTIVE To investigate risk factors for infections following acute cholecystitis and conduct a correlation analysis so as to reduce the risk of acute cholecystitis .METHODS Totally 246 patients with acute cholecystitis from Dec .2010 to Jan .2013 in our hospital were studied .The status of patients with infections was observed , and relevant information before admission was collected for univariate and multivariate logistic regression analyses .RESULTS Infections occurred in 54 out of 246 patients ,with the infection rate of 21 .95% . The univariate analysis showed age ,gender ,dietary habit ,diabetes ,liver cirrhosis ,white blood cell count ,fluid around the gallbladder ,and gallstones were the risk factors leading to infections following acute cholecystitis （P〈0 .05） .The further multivariate logistic regression analysis revealed that the patient＇s age ,gender ,dietary habit , diabetes ,white blood cell count , and gall stones were the independent risk factors leading to infections . CONCLUSION There are many risk factors influencing infections following acute cholecystitis . Early correct diagnosis and early surgery should be performed for elderly women with diabetes to reduce the incidence of infections .