膝关节周围骨巨细胞瘤的影像学特征及其与预后的关系

Correlation of MRI imaging features and surgical outcomes for the giant cell tumor of bone around the knee

目的探讨膝关节周围骨巨细胞瘤的影像学特征及其与预后的关系。方法 2010年9月到2013年12月诊治的骨巨细胞瘤患者230例,都给予了病理与MRI诊断,手术方式均为肿瘤刮除术,观察预后情况。结果在MRI表现中,230例患者病变中心性生长129例,偏心性101例;T1WI低或呈中等信号,T2WI呈等或稍高信号;信号环完整180例,无水肿80例。所有患者均完成手术,术后3个月的复发率为9.6%,总体优良率为90.9%。相关性分析显示,MRI影像学中的T2WI信号特征、软组织肿块形成、信号环完整性、病变生长特征与肿瘤复发和总体优良率有关(P<0.05)。结论膝关节周围骨巨细胞瘤患者可通过MRI诊断获得早期诊断,肿瘤刮除术的术后功能恢复比较好,复发率比较低,MRI的相关影像学特征与预后有明显相关性。

Objective To explore the correlation of MRI imaging features and surgical outcomes for the giant cell tumor of bone around the knee. Methods Selected 230 cases of giant cell tumor of bone a- round the knee from September 2010 to December 2013 in our hospital, all cases were given pathological and MRI diagnosis, the surgical methods were tumor curettage, the prognosis situation were observed. Re- suits In the MRI findings, there were 129 cases were lesions in the center of the growth, 101 cases of ec- centric; T1WI showed low or moderate signal, T2WI showed equal or slightly higher signal; The signal ring complete were 180 cases, 80 cases were without edema. All patients were completed the surgery, the recur- rence was 9.6% , the overall good rate was 90.9%. Correlation analysis showed the rF2WI imaging signal characteristics, soft tissue mass formation, the ring signal integrity, growth characteristics were significantly related to the prognosis of disease recurrence and overall good rate correlated （ P 〈 0. 05 ）. Conclusions The knee bone giant cell tumors can be obtained by MRI of early diagnosis, Tumor curettage had better post- operative functional recovery, the relapse rate was relatively low, the MRI imaging features were significant- ly correlated with the prognosis.