多层螺旋CT测定肺容积指标对慢性阻塞性肺疾病的诊断价值探讨

Value of Pulmonary Volume Index Measured by MDCT on the Diagnosis of Chronic Obstructive Pulmonary Disease

目的:分析多层螺旋CT检测慢性阻塞性肺疾病患者肺容积指数的准确性,探讨多层螺旋CT的诊断价值,为慢性阻塞性肺病的临床诊断提供可借鉴的方法。方法:选取2010年10月-2012年8月我院收治的慢性阻塞性肺疾病患者98例为观察组,另选取同期接受体检的健康志愿者70例为对照组。采用多层螺旋CT测定两组不同肺区的肺容积指标并与临床PFT指标进行相关性分析。结果:对照组与观察组的肺功能指标存在显著差异(P<0.05);观察组患者在不同肺区测定的Vin及上肺区Vin-Vex值无统计学意义(P>0.05);最大呼气末容积(Vex)、容积比(Vex/Vin)和肺容积变化比率[(Vin-Vex)/Vin]均呈显著差异,具有统计学意义(P<0.05);肺容积差(Vin-Vex)与各项PFT指标无相关性(P>0.05)。结论:64层螺旋CT肺容积成像对诊断COPD有预测意义,值得临床上进一步研究和推广。

Objective： To analyze the accuracy and diagnostic value of MDCT scanning on the diagnosis of the chronic obstructive pulmonary disease by calculating the lung volume index so as to provide some referential methods for the clinical field. Methods： 98 patients with chronic obstructive pulmonary disease who were treated in our hospital from October 2010 to August 2012 were selected as the observation group （COPD group）, and another 70 healthy people who were taken the examination were chosen to be the control group. Then the pulmonary lung volume index in different sections of patients were detected by means of the multilayer spiral CT, and the correlation of the clinical index and the PFT were analyzed. Results： There was statistically significant difference about the lung function index of patients between the two groups （P〈0.05）; When comparing with the control group, there was no statistically significant difference about the Vin and Vin-Vex at different sections of patients in the COPD group （P〉0.05）. There were statistically significant differences about the Vex, the Vex/Vin, the （Vin-Vex）/Vin and the various PFT indexes（P〈0.05）. Conclusions： It is indicated that the application of MDCT on the diagnosis of COPD could be used to predict lung volume for clinical research and extensions.