107例不明原因发热患者的诊断及病因分析

Diagnosis and analysis of pathogenesis for 107 patients with fever of unknown origin

目的探讨不明原因发热(FUO)的病因。方法对107例"发热待查"患者的临床资料进行回顾性分析,分析病例及诊断正确率。结果 107例中,102例做出了明确诊断,确诊率为95.3%;确诊的102例患者中,感染性疾病66例,占64.8%,非感染性疾病36例,占35.2%。结论 FUO的病因中,感染性疾病的发病率远高于非感染性疾病,而非感染性疾病中,结缔组织疾病及恶性肿瘤所占比例较高;全面、详细的临床资料采集及结合相关的辅助检查,大部分不明原因发热可以明确诊断。

Objective To investigate the pathogenesis of fever of unknown origin. Methods The clinical data of 107 casesof the patients with fever of unknown origin from November 2008 to November 2012 in our department were analyzed retro- spectively. Results In the 107cases, 102 patients were diagnosed clearly and the diagnosis rate was 95.3 %. In 102 cases, 66 cases were infection disease, accounting for 64.8 % ;while 36 cases were non infectious diseases, accounting for 35.2%. Conclusion In the etiology of FUO, the incidence of infections was much higher than that of the non infectious disease. In the cases of non infectious diseases, connective tissue diseases and malignant tumors accounted for a higher proportion. Through comprehensive and detailed clinical data acquisition and related auxiliary examination, most fever of unknown origin can be clearly diagnosed.