阻塞性睡眠呼吸暂停低通气综合征与甲状腺疾病的研究进展

The research progress of obstructive sleep apnea hypopnea syndrome and thyroid disease

OSAHS指睡眠状态下因上气道塌陷阻塞，反复发生呼吸暂停和／或低通气，造成间歇低氧、二氧化碳潴留、睡眠中断，从而引起心血管、内分泌、神经等多个系统的异常，严重影响生活甚至危及生命。近年来越来越多学者研究发现，OSAHS与甲状腺有一定关联并相互影响，某些甲状腺疾病如甲状腺功能减退与OSAHS关系密切，桥本甲状腺炎与OSAHS也存在一定联系，OSAHS又可以引起下丘脑一垂体一甲状腺轴及甲状腺本身功能的下降或异常，造成原有甲状腺疾病加重。本文就OSAHS与甲状腺关系的研究进展作一综述。

OSAHS is a disease characterized by partial or complete collapse of the upper airway while asleep accompanied by repeated hypopnea,apnea, resulting in intermittent hypoxia, carbon dioxide retention, sleep disruption, and it can cause cardiovascular, endocrine, nervous and other systems abnormalities, which seriously affects the quality of life and even leads to death. In recent years, more and more researchers have found OSAHS and thyroid have some relevance and interact with each other. Some thyroid disease such as hypothyroidism is closely related with OSAHS. Hashimoto ＇s thyroiditis can also be linked with OSAHS. OSAHS can make hypothalamic-pituitary-thyroid axis and thyroid function decreased, causing existied thyroid disease worse. In this paper, correlated research of OSAHS and thyroid disease was reviewed.