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柯萨奇病毒A6引起的伴有脱甲的手足口病病原学研究

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摘要 手足口病(hand,footandmouthdisease,HFMD)是由多种肠道病毒引起的常见急性传染病,以婴幼儿发病为主,少年儿童和成人感染后多不发病,但是具有一定的传染性[1]. 手足口病在许多文献中均有大量报道,但是柯萨奇病毒A6型(CVA6)引发的手足口病报道较少,并且伴有脱甲的报道更是少见.一般情况,引发HFMD的肠道病毒主要为肠道病毒71型(EV71)及柯萨奇病毒A16型(CVA16),其他肠道病毒如CVA4、CVA6、CVA10等也是该病的病原体[2].2013年5月在河北省张家口市蔚县境内出现一些手足口病患儿在恢复期伴有脱甲的病例.发病年龄在4月-5.5岁,有群体发病特点,以指(趾)甲变黑、脱落、再生新甲为主要临床表现,伴或不伴发热,脱甲时无皮疹及口腔疱疹,追问病史,在脱甲前1-2月80-90%的病例有手足口病史,咽拭子标本检测证实为柯萨奇病毒A组6型感染,追踪患儿预后良好.
出处 《中医学报》 CAS 2014年第B07期306-306,共1页 Acta Chinese Medicine
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参考文献8

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