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白细胞介素-10在莱姆病中的作用及其机制的研究进展 被引量：2

The effect of IL-10 on Lyme disease and its mechanism of action
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摘要 近年来,白细胞介素10(IL-10)与莱姆病的关系及其相关机制是目前研究的热点问题。如何利用IL-10的抗炎作用及对炎症的调控而对莱姆病采取积极有效的预防、治疗措施是近来研究的焦点。本文概述了白介素-10在莱姆病中的作用及其机制方面的研究进展。 Current studies are interested in the role of IL-10,a type of anti-inflammatory cytokine,in Lyme disease and its mechanism of action.Recent studies have focused on possible use of the anti-inflammatory action of and modulation of inflammation by IL-10 to actively and effectively prevent and treat Lyme disease.IL-10 and Lyme disease are reported to be related.To the extent known,however,few systematic studies have reported on the effect of IL-10 on Lyme disease,let alone on the detailed mechanism responsible.This paper reviews the effect of IL-10 on Lyme disease and its mechanism of action in order to provide new insight into the pathogenesis of Lyme disease and its treatment via an IL-10 intervention.
作者 李劲涛 冯时 李冰雪 宝福凯
机构地区 昆明医科大学神经科学研究所 云南省高校热带传染病重点实验室 云南省公共卫生与疾病防控协同创新中心 昆明医科大学热带医学研究所 昆明医科大学病原生物学与免疫学系
出处 《中国病原生物学杂志》 CSCD 北大核心 2014年第8期753-756,共4页 Journal of Pathogen Biology
基金 国家自然科学基金项目(No.81060134 81371835) 云南省自然科学基金项目(No.2010CD221 2011FB244 2012FB011 2013FZ057)
关键词 莱姆病 白细胞介素10 机制 综述 Lyme disease interleukin-10 mechanism review
分类号 R514 [医药卫生—内科学]
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参考文献37

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二级参考文献26

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中国病原生物学杂志
2014年 第8期

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