盐酸法舒地尔注射液治疗急性脑梗死疗效观察

Observation on the clinical effect of fasudil hydrochloride injection in the treatment of acute cerebral infarction

目的探讨盐酸法舒地尔注射液治疗急性脑梗死的临床疗效。方法 114例急性脑梗死患者随机分为观察组和对照组,观察组54例采用盐酸法舒地尔注射液治疗,对照组60例采用一般方法治疗。治疗前后对患者的临床神经功能缺损程度及生活质量进行评分,比较两组生活质量评分及总有效率。结果观察组和对照组治疗后神经功能缺损程度与治疗前比较差异均有统计学意义(P<0.05)。观察组和对照组在治疗后相比差异有统计学意义(P<0.05)。两组总有效率差异有统计学意义(P<0.05)。结论盐酸法舒地尔注射液能够有效改善患者的神经功能缺损,促进急性脑梗死患者康复,是治疗急性脑梗死的有效方法。

Objective To investigate the clinical effect of fasudil hydrochloride injection in the treatment of acute cerebral infarction. Methods A total of 114 patients with acute cerebral infarction were randomly divided into the treatment group and the control group. The 54 cases in treatment group were treated with fasudil hydrochloride injection, and the 60 cases in control group received conventional treatment. Scores of the clinical neurologic impairment degree before and after treatment and life quality were assessed. Comparison of life quality score and total effect rate was made between the two groups. Results The neurologic impairment degree after treatment had statistical significance in both groups, compared with the degree before treatment （P〈0.05）. The scores of neurologic impairment in the treatment group had statistical significance compared with those in the control group （P〈0.05）. The difference between the total effective rates of the two groups was statistically significant （P〈0.05）. Conclusion Fasudil hydrochloride injection can effectively improve the neurologic impairment symptoms and promote the recovery of acute cerebral infarction, and it is an effective clinical method for acute cerebral infarction.